Dimorphic expression of calbindin-D-28K in the medial basal hypothalamus from perinatal male and female rats

被引：30

作者：

Lephart, ED

机构：

[1] Department of Zoology, Cellular Biology Division, Brigham Young University, Provo

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1996年 / 96卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

hypothalamus amygdala; calbindin-D-28K; development; rat; sexual differentiation; western analysis;

D O I：

10.1016/0165-3806(96)00100-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Developmental expression of calbindin-D-28K (CALB) in the medial basal hypothalamic (MBH) and amygdaloid (AMY) regions was examined by Western analysis. Males displayed significantly higher CALB levels compared to females in the MBH (but not the AMY) from gestational day 17 through postnatal day 1. These data imply that androgens or other hormonal factors regulate MBH CALB expression which in turn may modulate sexually dimorphic brain structures by preventing cell loss during neuronal development.

引用

页码：281 / 284

页数：4

共 15 条

[1] GONADAL-STEROID INDUCTION OF STRUCTURAL SEX-DIFFERENCES IN THE CENTRAL NERVOUS-SYSTEM [J].