Prevalence of dementia and major dementia subtypes in Spanish populations: A reanalysis of dementia prevalence surveys, 1990-2008

被引：104

作者：

de Pedro-Cuesta, Jesus ^{[1
,2
]}

Virues-Ortega, Javier ^{[1
,2
]}

Vega, Saturio ^{[3
]}

Seijo-Martinez, Manuel ^{[4
]}

Saz, Pedro ^{[5
]}

Rodriguez, Fernanda ^{[6
]}

Rodriguez-Laso, Angel ^{[7
]}

Rene, Ramon ^{[8
]}

Perez de las Heras, Susana ^{[9
]}

Mateos, Raimundo ^{[10
]}

Martinez-Martin, Pablo ^{[1
,2
]}

Maria Manubens, Jose ^{[11
]}

Mahillo-Fernandez, Ignacio ^{[1
,2
]}

Lopez-Pousa, Secundino ^{[12
]}

Lobo, Antonio ^{[6
]}

Llinas Regla, Jordi ^{[12
]}

Gascon, Jordi ^{[8
]}

Jose Garcia, Francisco ^{[13
]}

Fernandez-Martinez, Manuel ^{[14
]}

Boix, Raquel ^{[1
,2
]}

Bermejo-Pareja, Felix ^{[15
]}

Bergareche, Alberto ^{[16
]}

Benito-Leon, Julian ^{[16
,17
]}

de Arce, Ana ^{[18
]}

Luis del Barrio, Jose ^{[1
,2
]}

机构：

[1] Carlos III Inst Publ Hlth, CIBERNED, Natl Ctr Epidemiol, Madrid, Spain

[2] Carlos III Inst Publ Hlth, Alzheimer Dis Res Unit, Madrid, Spain

[3] Primary Care Adm, Segovia, Spain

[4] Salnes Hosp, Neurol Unit, Pontevedra, Spain

[5] Univ Zaragoza, Dept Med & Psychiat, Zaragoza, Spain

[6] Segovia Hosp, Neurol Unit, Segovia, Spain

[7] Madrid Reg Hlth Author, Madrid, Spain

[8] Bellvitge Univ Teaching, Dept Neurol, Dementia Diag & Treatment Unit, Bellvitge, Spain

[9] Day Med Ctr, Llodio Hlth Ctr, Oroityu Getxo Vizcaya, Spain

[10] Univ Santiago de Compostela, Dept Psychiat, Santiago De Compostela, Spain

[11] Virgen Camino Hosp, Neurol Unit, Pamplona, Spain

[12] Hosp Santa Catarina, Inst Assistencia Sanitaria, Dementia Unit, Salt, Spain

[13] Barcelona Hosp, Barcelona, Spain

[14] Virgen Valle Geriatr Hosp, Geriatr Unit, Toledo, Spain

[15] Cruces Hosp, Day Med Ctr, Neurol Serv, Oroityu Getxo Vizcaya, Spain

[16] 12 Octubre Univ, Teaching Hosp, Dept Neurol, Madrid, Spain

[17] CIBERNED, Madrid, Spain

[18] Bidasoa Hondarribia Hosp, Dept Neurol, Guipuzcoa, Spain

来源：

BMC NEUROLOGY | 2009年 / 9卷

关键词：

DOOR-TO-DOOR; SOUTHERN EUROPEAN POPULATION; ALZHEIMERS-DISEASE; PARKINSONS-DISEASE; RISK-FACTORS; SPAIN; COMMUNITY; AGE; PROGRESSION; IMPAIRMENT;

D O I：

10.1186/1471-2377-9-55

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Background: This study describes the prevalence of dementia and major dementia subtypes in Spanish elderly. Methods: We identified screening surveys, both published and unpublished, in Spanish populations, which fulfilled specific quality criteria and targeted prevalence of dementia in populations aged 70 years and above. Surveys covering 13 geographically different populations were selected (prevalence period: 1990-2008). Authors of original surveys provided methodological details of their studies through a systematic questionnaire and also raw age-specific data. Prevalence data were compared using direct adjustment and logistic regression. Results: The reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimer's disease, 238 of vascular dementia). Results showed high variation in age-and sex-specific prevalence across studies. The reanalyzed prevalence of dementia was significantly higher in women; increased with age, particularly for Alzheimer's disease; and displayed a significant geographical variation among men. Prevalence was lowest in surveys reporting participation below 85%, studies referred to urban-mixed populations and populations diagnosed by psychiatrists. Conclusion: Prevalence of dementia and Alzheimer's disease in Central and North-Eastern Spain is higher in females, increases with age, and displays considerable geographic variation that may be method-related. People suffering from dementia and Alzheimer's disease in Spain may approach 600,000 and 400,000 respectively. However, existing studies may not be completely appropriate to infer prevalence of dementia and its subtypes in Spain until surveys in Southern Spain are conducted.

引用

页数：9

共 42 条

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