Laying hold on eternal life?

被引:5
作者
Wilmut, I [1 ]
Clark, J
Harley, CB
机构
[1] Roslin Inst, Roslin EH25 9PS, Midlothian, Scotland
[2] Geron Corp, Menlo Park, CA 94025 USA
关键词
D O I
10.1038/76430
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:599 / 600
页数:2
相关论文
共 10 条
[1]   Extension of life-span by introduction of telomerase into normal human cells [J].
Bodnar, AG ;
Ouellette, M ;
Frolkis, M ;
Holt, SE ;
Chiu, CP ;
Morin, GB ;
Harley, CB ;
Shay, JW ;
Lichtsteiner, S ;
Wright, WE .
SCIENCE, 1998, 279 (5349) :349-352
[2]   Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype [J].
Jiang, XR ;
Jimenez, G ;
Chang, E ;
Frolkis, M ;
Kusler, B ;
Sage, M ;
Beeche, M ;
Bodnar, AG ;
Wahl, GM ;
Tlsty, TD ;
Chiu, CP .
NATURE GENETICS, 1999, 21 (01) :111-114
[3]   Six cloned calves produced from adult fibroblast cells after long-term culture [J].
Kubota, C ;
Yamakuchi, H ;
Todoroki, J ;
Mizoshita, K ;
Tabara, N ;
Barber, M ;
Yang, XZ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (03) :990-995
[4]   Extension of cell life-span and telomere length in animals cloned from senescent somatic cells [J].
Lanza, RP ;
Cibelli, JB ;
Blackwell, C ;
Cristofalo, VJ ;
Francis, MK ;
Baerlocher, GM ;
Mak, J ;
Schertzer, M ;
Chavez, EA ;
Sawyer, N ;
Lansdorp, PM ;
West, MD .
SCIENCE, 2000, 288 (5466) :665-669
[5]   Absence of cancer-associated changes in human fibroblasts immortalized with telomerase [J].
Morales, CP ;
Holt, SE ;
Ouellette, M ;
Kaur, KJ ;
Yan, Y ;
Wilson, KS ;
White, MA ;
Wright, WE ;
Shay, JW .
NATURE GENETICS, 1999, 21 (01) :115-118
[6]   Analysis of telomere lengths in cloned sheep [J].
Shiels, PG ;
Kind, AJ ;
Campbell, KHS ;
Waddington, D ;
Wilmut, I ;
Colman, A ;
Schnieke, AE .
NATURE, 1999, 399 (6734) :316-317
[7]  
THOMASM, 2000, NAT BIOTECHNOL, V18, P39
[8]   Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span [J].
Vaziri, H ;
Benchimol, S .
CURRENT BIOLOGY, 1998, 8 (05) :279-282
[9]  
Wright WE, 1996, DEV GENET, V18, P173
[10]   Human endothelial cell life extension by telomerase expression [J].
Yang, JW ;
Chang, E ;
Cherry, AM ;
Bangs, CD ;
Oei, Y ;
Bodnar, A ;
Bronstein, A ;
Chiu, CP ;
Herron, GS .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (37) :26141-26148