Structural and functional considerations of the aminoacylation reaction

被引：272

作者：

Arnez, JG

Moras, D

机构：

[1] Laboratoire de Biologie Structurale, Inst. Genet. Biol. Molec. et Cell., CNRS/INSERM/ULP, 67404 Illkirch Cedex

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 06期

关键词：

D O I：

10.1016/S0968-0004(97)01052-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aminoacyl-tRNA synthetases (aaRS) bind their substrates - ATP, amino acids and tRNA - and stabilize putative transition states in the aminoacylation reaction. Here, we discuss the common and distinguishing structural and functional themes of the 20 known aaRS, which can be divided into two main classes (I and II) and into further subgroups on this basis.

引用

页码：211 / 216

页数：6

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