Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes

被引：132

作者：

Harrison, Tyler J. ^{[1
]}

Kozak, Jennifer A. ^{[1
]}

Corbella-Pane, Montserrat ^{[1
]}

Dake, Gregory R. ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 12期

关键词：

D O I：

10.1021/jo060382c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Either silver trifluoromethanesulfonate or a mixture of gold( I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted beta-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.

引用

页码：4525 / 4529

页数：5

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