Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology

被引：192

作者：

Droz, Jean-Pierre ^{[1
,2
]}

Aapro, Matti ^{[3
]}

Balducci, Lodovico ^{[4
]}

Boyle, Helen ^{[1
,2
]}

Van den Broeck, Thomas ^{[5
]}

Cathcart, Paul ^{[6
]}

Dickinson, Louise ^{[7
]}

Efstathiou, Eleni ^{[8
]}

Emberton, Mark ^{[7
]}

Fitzpatrick, John M. ^{[9
,10
]}

Heidenreich, Axel ^{[11
]}

Hughes, Simon ^{[12
]}

Joniau, Steven

Kattan, Michael ^{[13
]}

Mottet, Nicolas ^{[14
]}

Oudard, Stephane ^{[15
]}

Payne, Heather ^{[16
]}

Saad, Fred ^{[17
]}

Sugihara, Toru ^{[13
]}

机构：

[1] Univ Lyon 1, F-69365 Lyon, France

[2] Ctr Leon Berard, Dept Med Oncol, F-69373 Lyon, France

[3] Clin Genolier, Multidisciplinary Oncol Inst, Genolier, Switzerland

[4] Univ S Florida, Coll Med, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA

[5] Univ Hosp, Dept Urol, Leuven, Belgium

[6] Queen Mary Univ London, Dept Urol, London, England

[7] UCL, Div Surg & Intervent Sci, London, England

[8] Univ Athens, Sch Med, Dept Clin Therapeut, GR-11527 Athens, Greece

[9] Irish Canc Soc, Dublin, Ireland

[10] Univ Coll Dublin, Dublin 2, Ireland

[11] Rhein Westfal TH Aachen, Dept Urol, Aachen, Germany

[12] Guys & St Thomas NHS Trust, London, England

[13] Case Western Reserve Univ, Cleveland Clin, Lerner Coll Med, Dept Quantitat Hlth Sci, Cleveland, OH 44106 USA

[14] Univ Hosp, St Etienne, France

[15] Georges Pompidou Hosp, Dept Oncol, Paris, France

[16] Univ Coll London Hosp, London, England

[17] Ctr Hosp Univ Montreal, Urooncol Clin, Montreal, PQ, Canada

来源：

LANCET ONCOLOGY | 2014年 / 15卷 / 09期

关键词：

NEOADJUVANT ANDROGEN DEPRIVATION; SPARING RADICAL PROSTATECTOMY; MITOXANTRONE PLUS PREDNISONE; RANDOMIZED-TRIAL; ELDERLY-PATIENTS; CHEMOTHERAPY TOXICITY; ABIRATERONE ACETATE; INCREASED SURVIVAL; RISK; RADIOTHERAPY;

D O I：

10.1016/S1470-2045(14)70018-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

In 2010, the International Society of Geriatric Oncology (SIOG) developed treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013, a new multidisciplinary SIOG working group was formed to update these recommendations. The consensus of the task force is that older men with prostate cancer should be managed according to their individual health status, not according to age. On the basis of a validated rapid health status screening instrument and simple assessment, the task force recommends that patients are classed into three groups for treatment: healthy or fit patients who should have the same treatment options as younger patients; vulnerable patients with reversible impairment who should receive standard treatment after medical intervention; and frail patients with non-reversible impairment who should receive adapted treatment.

引用

页码：E404 / E414

页数：11

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