Remarkable structural variation within fatty acid megasynthases

被引：14

作者：

Cronan, JE ^{[1
]}

机构：

[1] Univ Illinois, Dept Microbiol & Biochem, Urbana, IL 61801 USA

来源：

NATURE CHEMICAL BIOLOGY | 2006年 / 2卷 / 05期

关键词：

D O I：

10.1038/nchembio0506-232

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structures of two chain-building megasynthases, the fatty acid synthases of mammals and fungi, have recently been reported. Although both are composed of modules derived from the discrete enzymes that catalyze bacterial fatty acid synthesis, the two synthases have dramatically different architectures.

引用

页码：232 / 234

页数：4

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