Cellular orchestration of T cell priming in lymph nodes

被引:21
作者
Breart, Beatrice [1 ]
Bousso, Philippe [1 ]
机构
[1] Inst Pasteur, INSERM, U668, G5 Dynam Reponses Immunes, F-75724 Paris 15, France
关键词
D O I
10.1016/j.coi.2006.05.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 [免疫学];
摘要
Progress made in visualizing T cell responses in vivo and at the single cell level has revealed an unexpected level of complexity in the orchestration of T cell activation in lymph nodes. The choreography that leads to the initiation of a T cell response involves multiple cellular actors, and is intrinsically influenced by their motility and their mode of cell-cell interactions. Recent studies have begun to depict the cellular orchestration of T cell priming and to analyze the way it could influence the outcome of T cell responses.
引用
收藏
页码:483 / 490
页数:8
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