The march of structural biology

被引：42

作者：

Campbell, ID ^{[1
]}

机构：

[1] Univ Oxford, Dept Biochem, Oxford OX1 3QU, England

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 05期

基金：

英国工程与自然科学研究理事会; 英国惠康基金; 英国医学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1038/nrm800

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

One hundred years ago, we knew very little about biological macromolecules and had no tools available to study their structure. Structural biology is now a mature science. New structures are being solved at an ever-increasing rate and there are important new initiatives to determine all the protein folds that are used by biological systems (structural genomics). This article traces some of the key developments in the field.

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收藏

页码：377 / 381

页数：5

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