Effects of various levels of dietary Artemisia abyssinica leaves on rats

被引：13

作者：

Adam, SEI ^{[1
]}

Al-Qarawi, AA ^{[1
]}

Elhag, EA ^{[1
]}

机构：

[1] King Saud Univ, Coll Agr & Vet Med, Buraidh, Al Qassim, Saudi Arabia

来源：

LABORATORY ANIMALS | 2000年 / 34卷 / 03期

关键词：

Artemisia abyssinica; hepatotoxicity; nephrotoxicity; rats;

D O I：

10.1258/002367700780384744

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 [兽医学];

摘要：

Artemisia abyssinica leaves, a traditional medicine for the treatment of various disorders, were fed to male Wistar rats at 2% and 10% of the standard diet for 6 weeks. A 2% A. abyssinica leaf diet was not toxic to rats. Depression in growth, hepatopathy and nephropathy were observed in rats fed a diet containing 10% of A. abyssinica leaves. These findings were accompanied by leukopenia, anaemia and alterations of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma glutamyl transferase (GGT) activities with changes in concentrations of total protein, albumin, cholesterol and urea.

引用

页码：307 / 312

页数：6