Monoclonal antibodies as therapeutics in oncology

被引：71

作者：

Trikha, M ^{[1
]}

Yan, L ^{[1
]}

Nakada, MT ^{[1
]}

机构：

[1] Centocor Oncol Res, Malvern, PA 19355 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 06期

关键词：

D O I：

10.1016/S0958-1669(02)00348-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The specificity of antibodies has been harnessed to target cancer cells and the first therapeutic antibodies for use in oncology are now finding application in the clinic. Studies are currently under way to develop new and improved antibodies. Recent developments have been made in the identification of novel targets, including the use of genomic and proteomic technologies. Several methods are also being developed to enhance antibody efficacy.

引用

页码：609 / 614

页数：6

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