Stressed marrow: FoxOs stem tumour growth

被引：11

作者：

Coffer, Paul J.

Burgering, Boudewijn M. T.

机构：

[1] Univ Med Ctr, Dept Immunol, NL-3584 EA Utrecht, Netherlands

[2] Univ Med Ctr, Physiol Chem Lab, NL-3584 CG Utrecht, Netherlands

来源：

NATURE CELL BIOLOGY | 2007年 / 9卷 / 03期

关键词：

D O I：

10.1038/ncb0307-251

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Although the molecular machinery controlling aging has been well studied in lower organisms, it is unclear whether these mechanisms are conserved in mammals. A recent study supports a role for an evolutionarily conserved transcriptional pathway in maintaining the unlimited lifespan of haematopoietic stem cells.

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收藏

页码：251 / 253

页数：4

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