Adsorption and activity of proteins onto mesoporous silica

被引:88
作者
Deere, J [1 ]
Magner, E [1 ]
Wall, JG [1 ]
Hodnett, BK [1 ]
机构
[1] Univ Limerick, Dept Chem & Environm Sci, Mat & Surface Sci Inst, Limerick, Ireland
关键词
adsorption/desorption; mesoporous; peroxidative activity;
D O I
10.1023/A:1022156405117
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The adsorption and activity of cytochrome c onto two different MCM-41 materials, MCM-41/28 and MCM-41/45 with average pore diameters of 28 and 45 Angstrom respectively, is presented. Nitrogen gas adsorption/desorption isotherms before and after protein adsorption, and peroxidative activity profiles of the adsorbed protein demonstrate that the protein is adsorbed into the mesoporosity and remains active. The adsorption of a range of different proteins onto both MCM-41/28 and 45 shows how protein properties affect adsorption.
引用
收藏
页码:19 / 23
页数:5
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