The RNA polymerase II general elongation factors

被引：120

作者：

Reines, D ^{[1
]}

Conaway, JW ^{[1
]}

Conaway, RC ^{[1
]}

机构：

[1] OKLAHOMA MED RES FDN,PROGRAM MOL & CELL BIOL,OKLAHOMA CITY,OK 73104

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 09期

关键词：

D O I：

10.1016/0968-0004(96)10045-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthesis of eukaryotic messenger RNA by RNA polymerase II is governed by the concerted action of a set of general transcription factors that control the activity of polymerase during both the initiation and elongation stages of transcription. To date, five general elongation factors [P-TEFb, SII, TFIIF, Elongin (SIII) and ELL] have been defined biochemically. Here, we discuss these transcription factors and their roles in controlling the activity of the RNA polymerase II elongation complex.

引用

页码：351 / 355

页数：5

共 37 条

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