A new synthesis of 3-carboxy-2,5-disubstituted furans and their conversion to 5-vinyl derivatives

被引：24

作者：

Marshall, JA ^{[1
]}

Zou, D ^{[1
]}

机构：

[1] Univ Virginia, Dept Chem, Charlottesville, VA 22904 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 09期

关键词：

cyclization; furans; diones; isomerization;

D O I：

10.1016/S0040-4039(99)02290-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new route to the title compounds is described. The key transformation involves treatment of a 2-(4-keto-2-alkynyl)-3-ketobutanoate with silica gel or Et3N to effect ring closure and subsequent double bond isomerization. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：1347 / 1350

页数：4

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