Organocatalytic one-pot asymmetric synthesis of functionalized tricyclic carbon frameworks from a triple-cascade/Diels-Alder sequence

被引：243

作者：

Enders, Dieter ^{[1
]}

Huettl, Matthias R. M. ^{[1
]}

Runsink, Jan ^{[1
]}

Raabe, Gerhard ^{[1
]}

Wendt, Bianca ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 03期

关键词：

asymmetric synthesis; cycloaddition; domino reactions; multicomponent reactions; organocatalysis;

D O I：

10.1002/anie.200603434

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Hitting the teens! Five C-C bonds and eight stereocenters were formed in a one-pot asymmetric multicomponent domino reaction, which led to the functionalized tricyclic diterpenoid-type core structures (see scheme, IMDA = intramolecular Diels-Alder reaction). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：467 / 469

页数：3

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