Retention, distribution, and effects of intraosseously administered ibandronate in the infarcted femoral head

被引：44

作者：

Aya-ay, James

Athavale, Sanjay

Morgan-Bagley, Stephanie

Bian, Haikuo

Bauss, Frieder

Kim, Harry K. W. ^{[1
]}

机构：

[1] Shriners Hosp Children, Tampa, FL USA

[2] Pharma Res Penzberg, Roche Diagnost, Penzberg, Germany

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 01期

关键词：

bisphosphonate; ibandronate; intraosseous; osteonecrosis; Legg-Calve-Perthes disease;

D O I：

10.1359/JBMR.060817

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

The local distribution, retention, and effects of intraosseous administration of ibandronate in the infarcted femoral heads were studied. Intraosseous administration effectively delivered and distributed ibandronate in the infarcted femoral heads and decreased the femoral head deformity in a large animal model of Legg-Calve-Perthes disease.

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页码：93 / 100

页数：8

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