p53 and cancer therapy: a double-edged sword

被引：30

作者：

McGill, G

Fisher, DE

机构：

[1] Dana Farber Canc Inst, Div Pediat Hematol Oncol, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Grad Program Biol & Biomed Sci, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Boston, MA 02115 USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1999年 / 104卷 / 03期

关键词：

D O I：

10.1172/JCI7861

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：223 / 225

页数：3

共 21 条

[1]

Ahnen DJ, 1998, CANCER RES, V58, P1149

[2]

Benhattar J, 1996, INT J CANCER, V69, P190, DOI 10.1002/(SICI)1097-0215(19960621)69:3<190::AID-IJC7>3.0.CO

[3]

2-V

[4]

Brown JM, 1999, CANCER RES, V59, P1391

[5] Disruption of p53 in human cancer cells alters the responses to therapeutic agents [J].

Bunz, F ;

Hwang, PM ;

Torrance, C ;

Waldman, T ;

Zhang, YG ;

Dillehay, L ;

Williams, J ;

Lengauer, C ;

Kinzler, KW ;

Vogelstein, B .

JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (03) :263-269

[6] P53-DEPENDENT APOPTOSIS IN THE ABSENCE OF TRANSCRIPTIONAL ACTIVATION OF P53-TARGET GENES [J].

CAELLES, C ;

HELMBERG, A ;

KARIN, M .

NATURE, 1994, 370 (6486) :220-223

[7] Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system [J].

Ding, HF ;

McGill, G ;

Rowan, S ;

Schmaltz, C ;

Shimamura, A ;

Fisher, DE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (43) :28378-28383

[8] INDUCTION OF APOPTOSIS IN FIBROBLASTS BY C-MYC PROTEIN [J].

EVAN, GI ;

WYLLIE, AH ;

GILBERT, CS ;

LITTLEWOOD, TD ;

LAND, H ;

BROOKS, M ;

WATERS, CM ;

PENN, LZ ;

HANCOCK, DC .

CELL, 1992, 69 (01) :119-128

[9] A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS [J].

FEARON, ER ;

VOGELSTEIN, B .

CELL, 1990, 61 (05) :759-767

[10] APOPTOSIS IN CANCER-THERAPY - CROSSING THE THRESHOLD [J].

FISHER, DE .

CELL, 1994, 78 (04) :539-542

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