Chiral recognition of bilirubin by polymeric nanoparticles

被引：5

作者：

Chung, TW

Cho, KY

Nah, JW

Akaike, T

Cho, CS ^{[1
]}

机构：

[1] Seoul Natl Univ, Sch Agr Biotechnol, Suwon 441744, South Korea

[2] Sunchon Natl Univ, Dept Polymer Sci & Engn, Sunchon 540742, South Korea

[3] Tokyo Inst Technol, Fac Biosci & Biotechnol, Yokohama, Kanagawa 2268501, Japan

来源：

LANGMUIR | 2002年 / 18卷 / 16期

关键词：

D O I：

10.1021/la020069f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The induced circular dichroism (ICD) and chiral recognition of bilirubin by polymeric nanoparticales was studied. The circular dichroism spectra were measured at room temperature using a spectropolarimeter equipped with a quartz cell having a path of 10 mm. The results showed that the hydrophobicity poly(γ-benzyl L-glutamate) core in the nanoparticles provided an enantioselective chiral microenvironment for the M-helicity enantiomer bilirubin stabilized through the intramolecularly hydrogen-bonded conformation.

引用

收藏

页码：6462 / 6464

页数：3

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