Balancing muscle hypertrophy and atrophy

被引：98

作者：

Hoffman, EP ^{[1
]}

Nader, GA ^{[1
]}

机构：

[1] Childrens Natl Med Ctr, Med Genet Res Ctr, Washington, DC 20010 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 06期

关键词：

D O I：

10.1038/nm0604-584

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The body carefully balances muscle atrophy and muscle hypertrophy in response to stimuli such as starvation or immobilization. Three new studies point to Akt1 phosphorylation of the transcription factor Foxo as a central regulator of this balance.

引用

页码：584 / 585

页数：2

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