Visual stimulation of saccades in magnetically tethered Drosophila

被引:91
作者
Bender, John A. [1 ]
Dickinson, Michael H. [1 ]
机构
[1] CALTECH, Div Biol, Pasadena, CA 91125 USA
关键词
Drosophila; saccade; vision;
D O I
10.1242/jeb.02369
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Flying fruit flies, Drosophila melanogaster, perform 'body saccades', in which they change heading by about 90 in roughly 70 ms. In free flight, visual expansion can evoke saccades, and saccade-like turns are triggered by similar stimuli in tethered flies. However, because the fictive turns in rigidly tethered flies follow a much longer time course, the extent to which these two behaviors share a common neural basis is unknown. A key difference between tethered and free flight conditions is the presence of additional sensory cues in the latter, which might serve to modify the time course of the saccade motor program. To study the role of sensory feedback in saccades, we have developed a new preparation in which a fly is tethered to a fine steel pin that is aligned within a vertically oriented magnetic field, allowing it to rotate freely around its yaw axis. In this experimental paradigm, flies perform rapid turns averaging 35 m 80 ms, similar to the kinematics of free flight saccades. Our results indicate that tethered and free flight saccades share a common neural basis, but that the lack of appropriate feedback signals distorts the behavior performed by rigidly fixed flies. Using our new paradigm, we also investigated the features of visual stimuli that elicit saccades. Our data suggest that saccades are triggered when expanding objects reach a critical threshold size, but that their timing depends little on the precise time course of expansion. These results are consistent with expansion detection circuits studied in other insects, but do not exclude other models based on the integration of local movement detectors.
引用
收藏
页码:3170 / 3182
页数:13
相关论文
共 54 条
[1]  
AUTRUM H., 1958, EXPTL CELL RES SUPPL, V5, P426
[2]   Chasing a dummy target: smooth pursuit and velocity control in male blowflies [J].
Boeddeker, N ;
Kern, R ;
Egelhaaf, M .
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2003, 270 (1513) :393-399
[3]  
BONHAG PF, 1948, MEM CORNELL U AGR EX, V285, P3
[4]   PRINCIPLES OF VISUAL-MOTION DETECTION [J].
BORST, A ;
EGELHAAF, M .
TRENDS IN NEUROSCIENCES, 1989, 12 (08) :297-306
[5]   HOW DO FLIES LAND [J].
BORST, A .
BIOSCIENCE, 1990, 40 (04) :292-299
[6]   VISUAL INFORMATION-PROCESSING IN THE FLYS LANDING SYSTEM [J].
BORST, A ;
BAHDE, S .
JOURNAL OF COMPARATIVE PHYSIOLOGY A-SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 1988, 163 (02) :167-173
[7]   Visual input to the efferent control system of a fly's "gyroscope" [J].
Chan, WP ;
Prete, F ;
Dickinson, MH .
SCIENCE, 1998, 280 (5361) :289-292
[8]   VISUAL CONTROL OF FLIGHT BEHAVIOR IN HOVERFLY, SYRITTA-PIPIENS L [J].
COLLETT, TS ;
LAND, MF .
JOURNAL OF COMPARATIVE PHYSIOLOGY, 1975, 99 (01) :1-66
[9]   RELATIONSHIP BETWEEN BODY ANGLE AND FLIGHT SPEED IN FREE-FLYING DROSOPHILA [J].
DAVID, CT .
PHYSIOLOGICAL ENTOMOLOGY, 1978, 3 (03) :191-195
[10]   Haltere-mediated equilibrium reflexes of the fruit fly, Drosophila melanogaster [J].
Dickinson, MH .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 1999, 354 (1385) :903-916