Experimental models of Schistosoma mansoni infection

被引：88

作者：

Cheever, AW

Lenzi, JA

Lenzi, HL

Andrade, ZA

机构：

[1] Fiocruz MS, Ctr Pesquisas Goncalo Moniz, Lab Patol Expt, BR-40295001 Salvador, BA, Brazil

[2] Biomed Res Inst, Rockville, MD 20852 USA

[3] Fiocruz MS, Inst Oswaldo Cruz, Dept Patol, BR-21045900 Rio De Janeiro, Brazil

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2002年 / 97卷 / 07期

关键词：

Schistosoma mansoni; experimental models; schistosomiasis;

D O I：

10.1590/S0074-02762002000700002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Experimental models of Schistosoma mansoni infections in mammals have contributed greatly to our understanding of the pathology and pathogenesis of infection. We consider here hepatic and extrahepatic disease in models of acute and chronic infection. Experimental schistosome infections have also contributed more broadly to our understanding of granulomatous inflammation and our understanding of Th1 versus Th2 related inflammation and particularly to Th2-mediated fibrosis of the liver.

引用

收藏

页码：917 / 940

页数：24

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