Interim analysis of the phase 1a/b study of chimeric fibril-reactive monoclonal antibody 11-1F4 in patients with AL amyloidosis

被引:42
作者
Edwards, Camille V. [1 ]
Gould, Julia [2 ]
Langer, Arielle L. [3 ]
Mapara, Markus [2 ]
Radhakrishnan, Jai [4 ]
Maurer, Mathew S. [5 ]
Raza, Shahzad [2 ]
Mears, John G. [2 ]
Wall, Jonathan [6 ]
Solomon, Alan [6 ]
Lentzsch, Suzanne [2 ]
机构
[1] Harlem Hosp Med Ctr, Dept Med, New York, NY USA
[2] Columbia Univ, Med Ctr, Div Hematol Oncol, 161 Ft Washington Ave, New York, NY 10032 USA
[3] Icahn Sch Med Mt Sinai, Div Hematol Oncol, New York, NY 10029 USA
[4] Columbia Univ, Med Ctr, Div Nephrol, New York, NY USA
[5] Columbia Univ, Med Ctr, Div Cardiol, New York, NY USA
[6] Univ Tennessee, Grad Sch Med, Knoxville, TN USA
来源
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS | 2017年 / 24卷
关键词
DEPOSITS;
D O I
10.1080/13506129.2017.1292900
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
引用
收藏
页码:58 / 59
页数:2
相关论文
共 5 条
[1]
Antibody-mediated resolution of light chain-associated amyloid deposits [J].
Hrncic, R ;
Wall, J ;
Wolfenbarger, DA ;
Murphy, CL ;
Schell, M ;
Weiss, DT ;
Solomon, A .
AMERICAN JOURNAL OF PATHOLOGY, 2000, 157 (04) :1239-1246
[2]
A staging system for renal outcome and early markers of renal response to chemotherapy in AL amyloidosis [J].
Palladini, Giovanni ;
Hegenbart, Ute ;
Milani, Paolo ;
Kimmich, Christoph ;
Foli, Andrea ;
Ho, Anthony D. ;
Rosin, Marta Vidus ;
Albertini, Riccardo ;
Moratti, Remigio ;
Merlini, Giampaolo ;
Schoenland, Stefan .
BLOOD, 2014, 124 (15) :2325-2332
[3]
New Criteria for Response to Treatment in Immunoglobulin Light Chain Amyloidosis Based on Free Light Chain Measurement and Cardiac Biomarkers: Impact on Survival Outcomes [J].
Palladini, Giovanni ;
Dispenzieri, Angela ;
Gertz, Morie A. ;
Kumar, Shaji ;
Wechalekar, Ashutosh ;
Hawkins, Philip N. ;
Schoenland, Stefan ;
Hegenbart, Ute ;
Comenzo, Raymond ;
Kastritis, Efstathios ;
Dimopoulos, Meletios A. ;
Jaccard, Arnaud ;
Klersy, Catherine ;
Merlini, Giampaolo .
JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (36) :4541-4549
[4]
Solomon A, 2003, CLIN CANCER RES, V9, p3831S
[5]
Radioimmunodetection of amyloid deposits in patients with AL amyloidosis [J].
Wall, Jonathan S. ;
Kennel, Stephen J. ;
Stuckey, Alan C. ;
Long, Misty J. ;
Townsend, David W. ;
Smith, Gary T. ;
Wells, Karen J. ;
Fu, Yitong ;
Stabin, Michael G. ;
Weiss, Deborah T. ;
Solomon, Alan .
BLOOD, 2010, 116 (13) :2241-2244