An evolutionary heterogeneity model of late-life fecundity in Drosophila

被引:23
作者
Mueller, Laurence D. [1 ]
Rauser, Casandra L. [1 ]
Rose, Michael R. [1 ]
机构
[1] Univ Calif Irvine, Dept Ecol & Evolut Biol, Irvine, CA 92697 USA
关键词
aging; Drosophila; fecundity plateau; late life; natural selection;
D O I
10.1007/s10522-006-9042-x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 [法学]; 0303 [社会学]; 100203 [老年医学];
摘要
There is now a significant body of research that establishes the deceleration of mortality rates in late life and their ultimate leveling off on a late-life plateau. Natural selection has been offered as one mechanism responsible for these plateaus. The force of natural selection should also exert such effects on female fecundity. We have already developed a model of female fecundity in late life that incorporates the general predictions of the evolutionary model. The original evolutionary model predicts a decline in fecundity from a peak in early life, followed by a plateau with non-zero fecundity in late life. However, in Drosophila there is also a well-defined decline in fecundity among dying flies, here called the "death spiral". This effect produces heterogeneity between dying and non-dying flies. Here a hybrid evolutionary heterogeneity model is developed to accommodate both the evolutionary plateau prediction and the death spiral. It is shown that this evolutionary heterogeneity model gives a much better fit to late-life fecundity data.
引用
收藏
页码:147 / 161
页数:15
相关论文
共 44 条
[1]
Optimality theory, Gompertz' law, and the disposable soma theory of senescence [J].
Abrams, PA ;
Ludwig, D .
EVOLUTION, 1995, 49 (06) :1055-1066
[2]
[Anonymous], 1996, Monte Carlo Concepts, Algorithms and Applications
[3]
Beard R.E., 1959, CIBA FDN COLLOQUIA A, V5, P302
[4]
Carey J.R., 2003, Longevity: The biology and demography of life span
[5]
CAREY JR, 1993, SCIENCE, V260, P1567, DOI 10.1126/science.260.5114.1567-a
[6]
CAREY JR, 1992, SCIENCE, V258, P457, DOI 10.1126/science.1411540
[8]
Chippindale Adam K., 2004, P413, DOI 10.1142/9789812567222_0034
[9]
The devil in the details of life-history evolution:: instability and reversal of genetic correlations during selection on Drosophila development [J].
Chippindale, AK ;
Ngo, AL ;
Rose, MR .
JOURNAL OF GENETICS, 2003, 82 (03) :133-145
[10]
PHENOTYPIC PLASTICITY AND SELECTION IN DROSOPHILA LIFE-HISTORY EVOLUTION .1. NUTRITION AND THE COST OF REPRODUCTION [J].
CHIPPINDALE, AK ;
LEROI, AM ;
KIM, SB ;
ROSE, MR .
JOURNAL OF EVOLUTIONARY BIOLOGY, 1993, 6 (02) :171-193