Characteristics of xanthan gum-based biodegradable superporous hydrogel

被引：128

作者：

Gils, Palapparambil Sunny ^{[1
]}

Ray, Debajyoti ^{[2
]}

Sahoo, Prafulla Kumar ^{[1
]}

机构：

[1] Utkal Univ, Dept Chem, Polymer Res Unit, Bhubaneswar 751004, Orissa, India

[2] Sri Jayadev Coll Pharmaceut Sci, PG Dept Pharmaceut, Bhubaneswar 752101, Orissa, India

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2009年 / 45卷 / 04期

关键词：

Biomaterials; Superporous hydrogel; Xanthan gum; Biodegradation; RELEASE; SODIUM; ACID;

D O I：

10.1016/j.ijbiomac.2009.07.007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

A novel biopolymer-based superporous hydrogel (SPH) was synthesized through chemical crosslinking by graft copolymerization of 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA) on to xanthan gum (XG) via redox initiator system of ammonium persulfate (APS) and N, N, N', N'-tetramethylethylenediamine (TMED), in the presence of N, N'-methylenebisacrylamide (MBA) crosslinking agent, sodium bicarbonate foaming agent, a triblock copolymer of polyoxyethylene/polyoxypropylene/polyoxyethylene as a foam stabilizer. Characterization of SPH was done by FT-IR, TGA, SEM, HPC and GCMS. The effects of pH and salinity on the swelling aptitude of the SPH were investigated along with its degradability in Streptococcus bovis medium. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：364 / 371

页数：8

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