Evaluation of serum and tissue levels of alpha-tocopherol

被引：14

作者：

Brandt, RB

Kaugars, GE

Riley, WT

Bei, RA

Silverman, S

Lovas, JGL

Dezzutti, BP

Chan, W

机构：

[1] VIRGINIA COMMONWEALTH UNIV, MED COLL VIRGINIA, DEPT PREVENT MED, RICHMOND, VA 23298 USA

[2] VIRGINIA COMMONWEALTH UNIV, MED COLL VIRGINIA, DEPT ORAL PATHOL, RICHMOND, VA 23298 USA

[3] VIRGINIA COMMONWEALTH UNIV, MED COLL VIRGINIA, DEPT PSYCHIAT, RICHMOND, VA 23298 USA

[4] VIRGINIA COMMONWEALTH UNIV, MED COLL VIRGINIA, DEPT PEDIAT NEPHROL, RICHMOND, VA 23298 USA

[5] UNIV CALIF SAN FRANCISCO, SCH DENT, DIV ORAL MED, SAN FRANCISCO, CA 94143 USA

[6] DALHOUSIE UNIV, FAC SCH DENT, HALIFAX, NS B3H 4HZ, CANADA

来源：

BIOCHEMICAL AND MOLECULAR MEDICINE | 1996年 / 57卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1006/bmme.1996.0009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This study was designed to test the effect of supplementation of several antioxidants, including alpha-tocopherol, on the clinical reduction of premalignant oral lesions. Samples of oral mucosa and serum were taken from baseline to 9 months of supplementation from patients with premalignant oral lesions and analyzed for alpha-tocopherol by HPLC. Statistical increases in both serum and tissue alpha-tocopherol were found after supplementation. There was no statistical relationship between alpha-tocopherol and beta-carotene levels. (C) 1996 Academic Press, Inc.

引用

页码：64 / 66

页数：3

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