Obesity, aerobic exercise, and vascular disease: The role of oxidant stress

被引：55

作者：

Fenster, CP

Weinsier, RL

Darley-Usmar, VM

Patel, RP

机构：

[1] Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA

[2] Univ Alabama Birmingham, Dept Nutr Sci, Birmingham, AL 35294 USA

[3] Univ Alabama Birmingham, Purdue UAB Bot Ctr, Birmingham, AL 35294 USA

[4] Univ Alabama Birmingham, Clin Nutr Res Ctr, Birmingham, AL 35294 USA

[5] Univ Alabama Birmingham, Ctr Free Radical Biol, Birmingham, AL 35294 USA

来源：

OBESITY RESEARCH | 2002年 / 10卷 / 09期

关键词：

physical activity; exercise; reactive oxygen species; nitric oxide; atherosclerosis;

D O I：

10.1038/oby.2002.131

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

FENSTER, CATHERINE P., ROLAND L. WEINSIER, VICTOR M. DARLEY-USMAR, AND RAKESH P. PATEL. Obesity, aerobic exercise, and vascular disease: the role of oxidant stress. Obes Res. 2002;10:964-968. Oxidant formation in the vasculature contributes to vascular disease and dysfunction associated with obesity. In contrast, exercise-dependent production of oxidants may stimulate adaptive responses that protect against the development of such diseases. In this review, we discuss current concepts in the biology of reactive oxygen and nitrogen species and how their function is modulated in the context of vascular disease, obesity, and aerobic exercise.

引用

页码：964 / 968

页数：5

共 49 条

[1]

Annual deaths attributable to obesity in the United States [J].