pH-Responsive mechanised nanoparticles gated by semirotaxanes

被引：61

作者：

Khashab, Niveen M. ^{[2
]}

Belowich, Matthew E. ^{[2
]}

Trabolsi, Ali ^{[2
]}

Friedman, Douglas C. ^{[2
]}

Valente, Cory ^{[2
]}

Lau, Yuen ^{[1
]}

Khatib, Hussam A. ^{[2
]}

Zink, Jeffrey I. ^{[1
]}

Stoddart, J. Fraser ^{[2
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[2] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 36期

基金：

美国国家科学基金会;

关键词：

DRUG-DELIVERY; SILICA NANOPARTICLES; MESOPOROUS SILICA; SUPRAMOLECULAR NANOVALVE; MOLECULAR MACHINE; BINDING; PSEUDOROTAXANES; STIMULI; GUEST; NANOMEDICINE;

D O I：

10.1039/b910431c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A [2] pseudorotaxane-based mechanised nanoparticle system, which operates within an aqueous acidic environment, has been prepared and characterised; this integrated system affords both water-soluble stalk and ring components in an effort to improve the biocompatibility of these promising new drug delivery vehicles.

引用

页码：5371 / 5373

页数：3

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