Models for spatial polymerization dynamics of rod-like polymers

被引:19
作者
Edelstein-Keshet, L [1 ]
Ermentrout, GB
机构
[1] Univ British Columbia, Dept Math, Vancouver, BC V6T 1Z2, Canada
[2] Univ Pittsburgh, Dept Math, Pittsburgh, PA 15260 USA
关键词
actin polymerization; treadmilling; spatial distribution of actin; polymerization kinetics; mathematical models;
D O I
10.1007/s002850050005
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We investigate the polymerization kinetics of rod-like polymer filaments interacting with a distribution of monomer in one spatial dimension (e.g. along a nan ow tube). We consider a variety of possible cases. including: competition by the filament tips for the available monomer, and behaviour analogous to "treadmilling" in which the polymer adds subunits to one end and loses them at the ether end so as to maintain a constant length. Applications to biological polymers such as actin filaments and microtubules are discussed.
引用
收藏
页码:64 / 96
页数:33
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