Stereoselective Synthesis of α-Alkyl-β-keto Imides via Asymmetric Redox C-C Bond Formation between α-Alkyl-α-diazocarbonyl Compounds and Aldehydes

被引：59

作者：

Hashimoto, Takuya ^{[1
]}

Miyamoto, Hisashi ^{[1
]}

Naganawa, Yuki ^{[1
]}

Maruoka, Keiji ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 32期

关键词：

ACID-CATALYZED-REACTIONS; ETHYL DIAZOACETATE; ENANTIOSELECTIVE SYNTHESIS; AROMATIC-ALDEHYDES; ALDOL REACTIONS; PART I; ESTERS; CONSTRUCTION; ARYLDIAZOACETATES; FACILE;

D O I：

10.1021/ja903500w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric redox C-C bond formation between alpha-alkyl-alpha-diazocarbonyl compounds and aldehydes was developed as a practical and general method for the construction of alpha-alkyl-beta-keto imides having a chiral nonracemic tertiary stereogenic center.

引用

页码：11280 / +

页数：4

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