Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view

被引：127

作者：

Wells, AD ^{[1
]}

Malkovsky, M

机构：

[1] Univ Penn, Dept Med, Philadelphia, PA 19104 USA

[2] Univ Wisconsin, Sch Med, Ctr Comprehens Canc, Dept Med Microbiol & Immunol, Madison, WI 53706 USA

[3] Univ Wisconsin, Wisconsin Reg Primate Res Ctr, Madison, WI 53706 USA

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 03期

关键词：

D O I：

10.1016/S0167-5699(99)01558-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A broad range of studies has established that heat shock proteins (Hsps) potentially play a role,in tumor immunosurveillance. Here, Andrew Wells and Miroslav, Malkovsky highlight recent data that demonstrate a causal relationship between the expression of Hsps and tumor immunogenicity, and suggest several mechanisms by which Hsps might influence the capacity of a tumor to induce nn immune response.

引用

页码：129 / 132

页数：4

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