The cyanobacterium Nodularia in PCC 7804, of freshwater origin, produces [L-Har2]nodularin

被引：62

作者：

Beattie, KA

Kaya, K

Codd, GA ^{[1
]}

机构：

[1] Univ Dundee, Dept Biol Sci, Dundee DD1 4HN, Scotland

[2] Natl Inst Environm Studies, Environm Chem Div, Tsukuba, Ibaraki 3050053, Japan

来源：

PHYTOCHEMISTRY | 2000年 / 54卷 / 01期

关键词：

Nodularia PCC 7804; Nodularia sphaerocarpa; cyanobacteria; blue-green algae; nodularin;

D O I：

10.1016/S0031-9422(00)00045-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The cyanobacterium Nodularia PCC 7804, an axenic, non gas-vacuolate strain from a freshwater source, produces several metabolites with cyanobacterial hepatotoxin characteristics. The most abundant is a cyclic pentapeptide, [L-Homoarginine(2)]nodularin. [L-Har(2)]nodularin is of similar toxicity, in terms of bioassay in vivo, and the inhibition of protein phosphatase-1 in vitro to nodularin, which was present in lesser amounts in the cultures. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：57 / 61

页数：5

共 19 条

[1] Genetic, morphological, and toxicological variation among globally distributed strains of Nodularia (cyanobacteria) [J].