Determination of the minimal erythema dose and colorimetric measurements as indicators of skin sensitivity to UV-B radiation

被引:44
作者
Dornelles, S
Goldim, J
Cestari, T
机构
[1] Hlth & Envirom Dept Rio Grande do Sul, Dept Sanit Dermatol, Porto Alegre, RS, Brazil
[2] Hosp Clin Porto Alegre, Dept Dermatol, Porto Alegre, RS, Brazil
关键词
D O I
10.1562/YG-03-08.1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
There is a strong relation between chronic UV-B-induced sunburns and the development of skin cancer. Therefore, it is important to obtain a method that can be reproduced easily to detect individuals with similar skin color but different sensitiveness to sun exposure. The study evaluated 193 healthy volunteers (68% women; the average age was 38 years). They were divided into six groups of at least 30 subjects, according to skin type. The minimal erythema dose (MED) was assessed in two non-sun-exposed areas (thorax-infra-axillary area and on the buttocks), using a UV-B source (0.5 mW/cm(2)), with 2 openings of 1 cm, in increasing doses. The same areas were evaluated with a Minolta CR 300 Chromameter (L*a*b* system). The MED values ranged from 13 to 156 mJ/cm(2); the coordinate L* (brightness) ranged from 75.96 to 30.15. The correlation between the MED and the brightness was negative in both areas (Pearson's correlation r = -0.91, P < 0.05). Color measurements, especially brightness, can be used to quickly assess skin sensibility. Considering the MED, there is a substantial overlapping of adjacent phototypes, but they could be separated into two groups: more sensitive individuals (Types I, II, III and IV) and less sensitive ones (Types V and VI).
引用
收藏
页码:540 / 544
页数:5
相关论文
共 26 条
[1]  
ANDREASSI L, 1990, PHOTODERMATOL PHOTO, V7, P20
[2]   Practical applications of cutaneous colorimetry [J].
Andreassi, L ;
Flori, L .
CLINICS IN DERMATOLOGY, 1995, 13 (04) :369-373
[3]   Correlating skin type and minimum erythema dose [J].
Baron, ED ;
Stern, RS ;
Taylor, CR .
ARCHIVES OF DERMATOLOGY, 1999, 135 (10) :1278-1279
[4]   Effect of constitutional pigmentation on ultraviolet B-induced DNA damage in fair-skinned people [J].
Bykov, VJ ;
Marcusson, JA ;
Hemminki, K .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2000, 114 (01) :40-43
[5]  
Bykov VJ, 1998, CANCER RES, V58, P2961
[6]   RELEVANCE OF SKIN PHOTOTYPING TO A KOREAN POPULATION [J].
CHUNG, JH ;
KOH, WS ;
YOUN, JI .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1994, 19 (06) :476-478
[7]  
Damian DL, 1997, BRIT J DERMATOL, V136, P714
[8]   QUANTIFICATION OF SKIN COLOR IN PATIENTS UNDERGOING MAINTENANCE HEMODIALYSIS [J].
DELEIXHEMAUHIN, F ;
KREZINSKI, JM ;
RORIVE, G ;
PIERARD, GE .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1992, 27 (06) :950-953
[9]  
Diffey BL, 1999, PHOTODERMATOLOGY, P5
[10]   Assessing children's ultraviolet radiation exposure: The potential usefulness of a colorimeter [J].
Eckhardt, L ;
Mayer, JA ;
Creech, L ;
Johnston, MR ;
Lui, KJ ;
Sallis, JF ;
Elder, JP .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1996, 86 (12) :1802-1804