Kinetics of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in 271 laboratory-confirmed cases of SARS

被引:15
作者
He, ZP [1 ]
Dong, QM
Zhuang, H
Song, SJ
Peng, G
Luo, GX
Dwyer, DE
机构
[1] Peking Univ, Ctr Hlth Sci, Dept Microbiol, Beijing 100083, Peoples R China
[2] Beijing Ditan Hosp, Beijing 100011, Peoples R China
[3] Univ Kentucky, Coll Med, Dept Microbiol Mol Genet & Immunol, Lexington, KY 40536 USA
[4] Westmead Hosp, Inst Clin Pathol & Med Res, Ctr Infect Dis, Westmead, NSW 2145, Australia
[5] Westmead Hosp, Inst Clin Pathol & Med Res, Microbiol Lab Serv, Westmead, NSW 2145, Australia
关键词
D O I
10.1128/CDLI.11.4.792-794.2004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The sensitivities and specificities of an immunofluorescence assay and an enzyme immunoassay for detection of antibodies specific for severe acute respiratory syndrome coronavirus (SARS-CoV) were compared for 148 laboratory-con firmed SARS cases. The appearance and persistence of SARS-CoV-specific antibodies were assessed, with immunoglobulin G detected in 59% of samples collected within 14 days and persisting for 60 to 95 days after the onset of illness.
引用
收藏
页码:792 / 794
页数:3
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