Towards polyketide libraries: Iterative, asymmetric aldol reactions on a solid support

被引：52

作者：

Reggelin, M

Brenig, V

机构：

[1] Institut für Organische Chemie, Universität Frankfurt/Main, D-60439 Frankfurt/Main

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 38期

关键词：

D O I：

10.1016/0040-4039(96)01527-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A polymer bound aldehyde obtained from the oxidation of Wang's resin can be used as starter unit for iterative, asymmetric aldol reactions. The synthetic protocol relies on the boron enolate chemistry of D. A. Evans, the N-methoxy substituted amides of S. M. Weinreb and entails the opportunity for the generation of polyketide Libraries. Copyright (C) 1996 Elsevier Science Ltd

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页码：6851 / 6852

页数：2

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