Optimization of the do pant for the trace determination of polycyclic aromatic hydrocarbons by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry

被引：76

作者：

Itoh, Nobuyasu ^{[1
]}

Aoyagi, Yoshie ^{[1
]}

Yarita, Takashi ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, Natl Metrol Inst Japan, Tsukuba, Ibaraki 3058563, Japan

来源：

JOURNAL OF CHROMATOGRAPHY A | 2006年 / 1131卷 / 1-2期

关键词：

polycyclic aromatic hydrocarbons (PAHs); atmospheric pressure photoionization (APPI); dopant-assisted APPI (DA-APPI); LC/MS; dopant;

D O I：

10.1016/j.chroma.2006.08.091

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The composition of the dopant for the analysis of polycyclic aromatic hydrocarbons (PAHs) by liquid chromatography/dopant-assisted atmospheric-pressure photoionization/mass spectrometry under reversed-phase conditions was optimized to enhance the ionization efficiency for PAHs. The most suitable dopant was a toluene/anisole mixture (99.5:0.5, v/v) and it could improve limit of detections (LODs) to 0.79-168 ng mL(-1) (signal-to-noise (S/N) = 3) for 16 common PAHs. The LODs are 3.8-40 times lower than those obtained with toluene alone and are comparable to those obtained using gas chromatography/mass spectrometry. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：285 / 288

页数：4

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