Macrolide resistance in Belgian Streptococcus pneumoniae

被引：39

作者：

Lagrou, K

Peetermans, WE

Verhaegen, J

Van Lierde, S

Verbist, L

Van Eldere, J

机构：

[1] Katholieke Univ Leuven, Rega Inst Med Res, Infect Dis Grp, Dept Immunol & Microbiol, B-3000 Louvain, Belgium

[2] Katholieke Univ Leuven, Rega Inst Med Res, Infect Dis Grp, Dept Internal Med, B-3000 Louvain, Belgium

[3] Katholieke Univ Leuven, Rega Inst Med Res, Infect Dis Grp, Dept Paediat, B-3000 Louvain, Belgium

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2000年 / 45卷 / 01期

关键词：

D O I：

10.1093/jac/45.1.119

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The genetic basis of macrolide resistance was characterized in 59 Streptococcus pneumoniae isolates. All isolates were collected in 1995 and 1997 and were from invasive infections. The majority of the isolates (54 of 59 isolates) were erythromycin and clindamycin resistant (MLS(B)-phenotype) and carried the ermAM gene. Five isolates were erythromycin resistant but clindamycin susceptible (M-phenotype). Using PCR the mefE gene was detected in these five isolates. Contrary to the situation found in Canada and the USA, mefE-mediated erythromycin resistance in S. pneumoniae is uncommon in Belgium.

引用

页码：119 / 121

页数：3

共 9 条

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