A simple and efficient synthesis of (±)-mesembrine

被引:21
作者
Chavan, SP [1 ]
Khobragade, DA [1 ]
Pathak, AB [1 ]
Kalkote, UR [1 ]
机构
[1] Natl Chem Lab, Div Organ Chem Technol, Pune 411008, Maharashtra, India
关键词
alkaloids; Michael addition; Wittig reaction; protection; deprotection;
D O I
10.1016/j.tetlet.2004.05.021
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple and efficient synthesis of (+/-)-mesembrine I is described employing double Michael addition and as the key step in 18% overall yield. (C) 2004 Published by Elsevier Ltd.
引用
收藏
页码:5263 / 5265
页数:3
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