Oral IgA-IgG treatment of chronic non-specific diarrhoea in infants and children

被引：14

作者：

Casswall, TH

Hammarstrom, L

Veress, B

Nord, CE

Bogstedt, A

Brockstedt, U

Dahlstrom, KA

机构：

[1] HUDDINGE HOSP,KAROLINSKA INST,DEPT CLIN SCI,DIV PAEDIAT,S-14186 HUDDINGE,SWEDEN

[2] HUDDINGE HOSP,KAROLINSKA INST,DEPT IMMUNOL MICROBIOL PATHOL & INFECT DIS,S-14186 HUDDINGE,SWEDEN

来源：

ACTA PAEDIATRICA | 1996年 / 85卷 / 09期

关键词：

chronic non-specific diarrhoea; gut flora; infants and children; oral immunoglobulins;

D O I：

10.1111/j.1651-2227.1996.tb14231.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The effect of orally administered immunoglobulin (IgAbulin((R))) on chronic non-specific diarrhoea of infancy was studied in seven children, median age 26 (21-36) months and duration of diarrhoea 32 (18-84) weeks. Routine laboratory tests for malabsorption and small bowel biopsies were taken in all children before and after 3 weeks of IgAbulin((R)) treatment. The biopsy specimens were analysed with regard to histopathology, electronmicroscopy, immunohistochemistry and microbiology. The number of stools decreased from a median of 4.0 (3.0-5.0) to 1.5 (1.0-3.5) (p < 0.05) stools per day over the study period.

引用

页码：1126 / 1128

页数：3

共 15 条

[1] HUMORAL AND CELLULAR-IMMUNITY IN HUMANS STUDIED AT THE CELL LEVEL FROM BIRTH TO 2 YEARS OF AGE [J].