The antiquity of RNA-based evolution

被引：705

作者：

Joyce, GF

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

[3] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

NATURE | 2002年 / 418卷 / 6894期

基金：

美国国家航空航天局;

关键词：

D O I：

10.1038/418214a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

All life that is known to exist on Earth today and all life for which there is evidence in the geological record seems to be of the same form-one based on DNA genomes and proteins enzymes. Yet there are strong reasons to conclude that DNA- and protein-based life was preceded by a simpler life form based primarily on RNA. This earlier era is referred to as the 'RNA world', during which the genetic information resided in the sequence of RNA molecules and the phenotype derived from the catalytic properties of RNA.

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页码：214 / 221

页数：8

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