Integrin signaling: it's where the action is

被引：139

作者：

Damsky, CH

Ilic, D

机构：

[1] Univ Calif San Francisco, Sch Dent, Dept Stomatol, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Sch Dent, Dept Anat, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Sch Med, Dept Anat, San Francisco, CA 94143 USA

[4] Univ Calif San Francisco, Sch Med, Dept Stomatol, San Francisco, CA 94143 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(02)00368-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent advances highlight a critical role for integrin receptors for extracellular matrix in determining where in cells critical signals are transduced. Integrins are shown to activate signaling intermediates at specific surface membrane locations, to promote nuclear translocation of factors that activate gene transcription, and to recruit and augment the signaling power of receptors for growth factors.

引用

收藏

页码：594 / 602

页数：9

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