A new route to sulfonamides via intermolecular radical addition to pentafluorophenyl vinylsulfonate and subsequent aminolysis

被引：78

作者：

Caddick, S ^{[1
]}

Wilden, JD ^{[1
]}

Bush, HD ^{[1
]}

Wadman, SN ^{[1
]}

Judd, DB ^{[1
]}

机构：

[1] Univ Sussex, Ctr Biomol Design & Drug Dev, Brighton BN1 9QJ, E Sussex, England

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 15期

关键词：

D O I：

10.1021/ol026181m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Various radical species generated from either the corresponding iodo- or bromo- compounds and tri-n-butyltin hydride were added in an intermolecular fashion to the activated acceptor pentafluorophenyl vinylsulfonate. The products of each reaction were then subjected to aminolysis with a variety of different amines.

引用

页码：2549 / 2551

页数：3

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