Regulating the regulator of ROS production

被引：10

作者：

Bonini, Marcelo G. ^{[1
,2
,3
]}

Malik, Asrar B. ^{[1
,4
]}

机构：

[1] Univ Illinois, Coll Med, Dept Pharmacol, Chicago, IL 60612 USA

[2] Univ Illinois, Coll Med, Dept Med, Chicago, IL 60612 USA

[3] Univ Illinois, Coll Med, Dept Pathol, Chicago, IL 60612 USA

[4] Univ Illinois, Coll Med, Ctr Lung & Vasc Biol, Chicago, IL 60612 USA

来源：

CELL RESEARCH | 2014年 / 24卷 / 08期

关键词：

D O I：

10.1038/cr.2014.66

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Balancing inflammatory reactive oxygen species (ROS) production is essential for safely eliminating pathogenic microbes. The newly described protein Negative Regulator of ROS (NRROS) dampens ROS production by restricting NOX2 availability, and thus "cools-off" inflammation.

引用

页码：908 / 909

页数：2

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