Metabolic syndrome and gender differences in postprandial lipaemia

被引：36

作者：

Kolovou, Genovefa D.

Anagnostopoulou, Katherine K.

Pavlidis, Antonis N.

Salpea, Klelia D.

Iraklianou, Stella A.

Hoursalas, Ioannis S.

Mikhailidis, Dimitri P.

Cokkinos, Dennis V.

机构：

[1] Onassis Cardiac Surg Ctr, Cardiol Dept 1, Athens 17674, Greece

[2] Onassis Cardiac Surg Ctr, Dept Mol Biol, Athens 17674, Greece

[3] Univ London, Royal Free & Univ Coll Med Sch, Royal Free Hosp, Dept Clin Biochem,Vasc Dis Prevent Clin, London, England

[4] Tzanio State Hosp, Dept Med, Piraeus, Greece

来源：

EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION | 2006年 / 13卷 / 04期

关键词：

gender differences; metabolic syndrome; postprandial lipaemia;

D O I：

10.1097/01.hjr.0000224490.10845.26

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Postprandial hyperlipidaemia may be a predictor of vascular risk. Design We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n = 41) and women (n = 21) with metabolic syndrome (MetS). Methods Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load. Results Men showed a greater plasma TG response 8 h after the fat load (284 117 versus 224 +/- 126 mg/dl, P = 0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC. Conclusions Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.

引用

页码：661 / 664

页数：4

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