Protein production: feeding the crystallographers and NMR spectroscopists

被引:125
作者
Edwards, AM
Arrowsmith, CH
Christendat, D
Dharamsi, A
Friesen, JD
Greenblatt, JF
Vedadi, M
机构
[1] Ontario Canc Inst, Toronto, ON, Canada
[2] Univ Toronto, Banting & Best Dept Med Res, Toronto, ON, Canada
[3] Integrat Proteom, Toronto, ON, Canada
关键词
D O I
10.1038/80751
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the next few years. The purified proteins will be valuable reagents for the entire research community.
引用
收藏
页码:970 / 972
页数:3
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