Urea hydrogen peroxide determination in whole blood using europium tetracycline probe

被引：22

作者：

Courrol, Lilia C. ^{[1
]}

Bellini, Maria H.

Tarelho, Luiz V. G.

Silva, Flavia R. O.

Mansano, Ronaldo D.

Gomes, Laercio

Vieira, Nilson D., Jr.

Shor, Nestor

机构：

[1] FATEC SP, CEETEPS, Sao Paulo, Brazil

[2] IPEN, CNEN SP, Sao Paulo, Brazil

[3] EPUSP, LSI, Sao Paulo, Brazil

[4] Univ Fed Sao Paulo, Nefrol, Sao Paulo, Brazil

来源：

ANALYTICAL BIOCHEMISTRY | 2006年 / 355卷 / 01期

关键词：

lanthanides; optical sensor; glucose; urea hydrogen peroxide; tetracycline; energy transfer;

D O I：

10.1016/j.ab.2006.05.015

中图分类号：

Q5 [生物化学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We introduce the use of a lanthanide complex, tetracycline-europium, for the clinical diagnosis of urea hydrogen peroxide in human whole blood. The values obtained agree with the urea concentration variation verified in 49 patients, including 12 predialysis, 12 peritoneal, and 15 dialysis subjects, and 10 controls. This method is noninvasive and can help in the identification of renal and cardiac diseases. (c) 2006 Elsevier Inc. All rights reserved.

引用

收藏

页码：140 / 144

页数：5

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