Fatty liver, carotid disease and gallstones: A study of age-related associations

被引:54
作者
Lonardo, Amedeo [1 ]
Lombardini, Silvia [1 ]
Scaglioni, Federica [1 ]
Ballestri, Stefano [1 ]
Verrone, Anna Maria [1 ]
Bertolotti, Marco [1 ]
Carulli, Lucia [1 ]
Ganazzi, Dorval [1 ]
Carulli, Nicola [1 ]
Loria, Paola [1 ]
机构
[1] Univ Modena & Reggio Emilia, Azienda USL, Dept Internal Med Metab Endocrinol & Geriatr, Osped Baggiovara, I-41100 Modena, Italy
关键词
atherosclerosis; carotid; gallstones; intimamedia; thickening; fatty liver;
D O I
10.3748/wjg.v12.i36.5826
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
AIM: To evaluate carotid intima-media thickening (IMT) and plaques, gallstone disease (GD) and fatty liver (FL) as a function of age. METHODS: In 449 subjects, FL and carotid disease were assessed ultrasonographically. In a subgroup of 65/449 patients with non-alcoholic fatty liver disease (NAFLD), carotid disease, GD and associated factors were determined. RESULTS: FL of unspecified etiology was more common in younger and GD in older individuals. FL subjects had an increased prevalence of IMT and a decreased prevalence of plaques and manifested carotid disease earlier. Plaques were more common in subjects with GD. Age was an independent predictor of carotid disease outcome and FL was a protective factor for plaques. In NAFLD, there was an inverse correlation between body weight and age and the latter independently predicted carotid findings. CONCLUSION: Cardiovascular risk in patients with FL and NAFLD needs to be assessed as a function of age and body weight. (C) 2006 The WJG Press. All rights reserved.
引用
收藏
页码:5826 / 5833
页数:8
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