The regulation of bacterial transcription initiation

被引:734
作者
Browning, DF [1 ]
Busby, SJW [1 ]
机构
[1] Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England
基金
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词
D O I
10.1038/nrmicro787
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bacteria use their genetic material with great effectiveness to make the right products in the correct amounts at the appropriate time. Studying bacterial transcription initiation in Escherichia coli has served as a model for understanding transcriptional control throughout all kingdoms of life. Every step in the pathway between gene and function is exploited to exercise this control, but for reasons of economy, it is plain that the key step to regulate is the initiation of RNA-transcript formation.
引用
收藏
页码:57 / 65
页数:9
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