Vascular endothelial growth factor and its correlation with superficial bladder cancer recurrence rates and stage progression

被引：23

作者：

Jones, A ^{[1
]}

Crew, J

机构：

[1] John Radcliffe Hosp, Inst Mol Med, Mol Oncol Grp, Imperial Canc Res Fund, Oxford OX3 9DS, England

[2] Churchill Hosp, Specialist Registrars, Oxford OX3 7LJ, England

[3] Churchill Hosp, Dept Urol, Oxford OX3 7LJ, England

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2000年 / 27卷 / 01期

关键词：

D O I：

10.1016/S0094-0143(05)70247-0

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Angiogenesis is well established as an important component of tumor biology. The angiogenic stimulator, vascular endothelial growth factor (VEGF) is implicated, and indeed prognostic, in a number of tumor types. VEGF mRNA is prognostic for both recurrence and stage progression in superficial bladder cancer. Urinary estimation of VEGF can provide similar information. These findings highlight the importance of VEGF in bladder tumor pathogenesis and indicate a potential therapeutic target.

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页码：191 / +

页数：9

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