Synthesis of enantiomerically pure (+)- and (-)-protected 5-aminomethyl-1,3-oxazolidin-2-one derivatives from allylamine and carbon dioxide

被引：22

作者：

Fernandez, Isabelle ^{[1
]}

Munoz, Luis ^{[1
]}

机构：

[1] Univ Vigo, Fac Quim, Dept Quim Organ, Vigo 36210, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 17期

关键词：

D O I：

10.1016/j.tetasy.2006.08.006

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The stereoselective synthesis of enantiomerically pure (5R)- and (5S)-aminomethyl-oxazolidinones with different protecting groups have been carried out from an allyl amine as the source of the carbon backbone. The key reaction is the high yield iodiocyclization of enantiomerically pure allylphenethyl amine in the presence of carbon dioxide. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2548 / 2557

页数：10

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